![]() Growing evidence suggests that chronic pain may not always follow these pathways but may in fact find its genesis within these higher centers including the limbic system and the cortex. Acute pain usually begins with nociception or sensation and is transmitted by both the peripheral and central nervous system to higher centers for processing and perception and also for modulation of the incoming message. ![]() Pain is the chief reason patients visit physicians, and as such, it is incumbent upon us, regardless of specialty, to understand it. ![]() Knowing why and when to prescribe opioids for non-cancer pain, both acute and chronic, is facilitated by a basic knowledge of pain physiology (and psychology) and the treatment modalities that are best oriented toward those physiologic-and psychological-processes. ![]()
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